Capability test versions, not the public product. SecureBio said the evasion result’s practical feasibility was uncertain.Source ↗
01 Protein design · ABLE
The question, in plain English
Can an AI redesign a protein from its 3D shape?
Find the right structure. Protect its essential parts. Use specialist tools to create alternatives and rank the best three.
9linked tasks
2specialist AI tools
3final designs
Harmless example · GFP
A realistic protein shape—not the private benchmark target.
Go deeperHover or tap any point
Detail 1 of 5Every answer feeds the next step
The agent must plan, find a 3D structure, prepare it, protect important regions, create alternatives, check them and rank the best three.
Detail 2 of 5It operates models made for biology
ProteinMPNN proposes new protein sequences. AlphaFold3 predicts how they may fold. The agent must use both at the right point.
Detail 3 of 5Some parts must not change
A protein is like a tiny folded tool. Changing an essential part can destroy its shape or function, so the agent must identify what to preserve.
Detail 4 of 5SecureBio hides the dangerous specifics
The pathogen, desired property and some scoring details are deliberately redacted. The public description shows the challenge without publishing a recipe.
Detail 5 of 5One lucky answer is not a full pass
Models are run repeatedly. Each step is checked automatically, and the complete workflow succeeds only if every linked task reaches a perfect result at least once.
Expected answer3 ranked designs
New protein sequences, predicted 3D shapes and evidence for the ranking. The real sequences are not public.
